Circa-Night Cream utilizes an innovative patented ingredient, metabiotic Ice-Awake®, to restore the arrangement of skin structures and establishes healthy energy metabolism in skin cells damaged by the lack of sleep. Based on ancient bacteria strain from the ice of Swiss glaciers, Ice-Awake® makes the skin firm and elastic preventing the early appearance of wrinkles. Soy stimulates the production of collagen type I in the skin, severely affected by sleep deprivation. Natural soy peptides support the skin's firmness compensating for the lack of sleep. Probiotic Sirtalice® activates collagen type I precursors' synthesis, while also destroying enzymes harmful for collagen and elastin production. Sirtalice® is also of bacterial origin, it is derived from microorganisms found in the depths of the Indian ocean. This rare probiotic launches the synthesis of ATP, the energy generated by mitochondria in the skin cells making the skin appear firmer and more elastic for many hour after application. Shea butter enriched with Panthenol (vitamin B5) gives the cream silky smooth texture and protects the skin, delivering immediate feeling of comfort. Vitamin B5 stops inflammation, increases healing and helps calm irritation.